Also posted over at Paramedicine 101 (now at EMS Blogs) and at Research Blogging. Go check out the excellent material at these sites.
This is adding to what I wrote yesterday about the continuing failure of Masimo’s RAD-57. The RAD-57 does not demonstrate any kind of acceptable sensitivity or specificity to be marketed as a mass screening device – and especially not to screen firefighters to go back to fighting fire. This is just more evidence that the RAD-57 does not accurately measure carboxyhemoglobin (COHb).
Here is a report of a mass delusion that seems to have been compounded by the use of the Masimo RAD-57 non-invasive CO monitor. CO (Carbon monOxide) is a significant cause of poisoning in the US, but not relevant in this case. The RAD-57 incorrectly identified CO poisoning in half a dozen people who do not appear to have had any exposure to CO.
Sociogenic illness is a rare but well-described phenomenon. It involves a constellation of physical signs and symptoms without an organic cause in a group of individuals with a common ‘‘exposure’’ (1–8). It often occurs in the setting of large gatherings such as schools or when large numbers of people are living or working in close proximity.
I wrote about a different example of mass delision a couple of weeks ago. We underestimate our ability to delude ourselves, but we are great at self-delusion and we are most delusional in groups. No need for any objectivity. Just go with the feeling of a group.
Approximately 15 min into the mass, one child fainted, followed by another child. The children did not have any seizure activity and immediately awoke with normal mental status and were removed from the church. Within minutes, several more children reported a variety of complaints, including nausea, hand paresthesia, and dyspnea.
A poison strong enough to cause people to pass out, is not going to result in a return to normal mental status right away.
The ﬁre department initially evaluated the patients with complaints, including obtaining carboxyhemoglobin (COHb) oximetry and oxygen saturation readings from a hand-held portable Masimo® device (Masimo Corporation, Irvine, CA). At the scene, 6 patients were reported to have elevated COHb levels. As such, the church was closed and paramedics, as well as the city’s hazardous materials (HAZMAT) team, were called to the scene.
If only someone had told them that the RAD-57 doesn’t work, much of the chaos could have been avoided.
Blood COHb levels, obtained in all patients soon after arrival in the ED, ranged from 0.2% to 1.2% (mean 0.65%). The hospital laboratory reference range for COHb is < 1.5% for non-smokers and as high as 5% for smokers. However, this upper value can be much higher in heavy smokers (9). None of our patients had elevated blood COHb levels.
A magic diesel cure?
It’s a miracle!
In the ED, all patients had normal physical examinations, including neurologic and respiratory examinations.
Were their physical exams much different on scene?
Subsequent evaluation of the church, classrooms, and surrounding premises by ﬁre department and HAZMAT personnel found no evidence of carbon monoxide or any other toxicants.
The interesting part that is not well described is the initial response of the fire department. Almost always, they have atmospheric CO alarms on their gear. When a firefighter walks into a room with elevated CO, the alarm goes off. When there is a report of a possible CO exposure, a couple of fully geared up firefighters will investigate everywhere they can in a building, looking for areas where CO might be leaking and for areas where CO might have accumulated.
There is no mention of any finding of CO at any time on scene.
No – the RAD-57 is not an indication of the presence of CO.
The affected persons were sitting in various areas of the church and many of the unaffected individuals were sitting near affected persons. This variability is not consistent with a simple asphyxiant. Furthermore, several patients became symptomatic after leaving the church, which would not be seen with a simple asphyxiant.
Exposures to gasses should present with a predictable pattern. The people in the most heavily concentrated area should be the most affected, with the smallest people (generally children) and the most active people (also generally children) being more affected than the larger and less active people. That was not the case. This suggests MSI (Mass Sociogenic Illness, or mass delusion).
the escalation of symptoms and increased number of persons affected along with increasing ﬁre and ambulance presence is a common phenomenon in MSI, referred to as ‘‘line of sight transmission.’’
Even if it appears obvious that this is a mass delusion, we should provide treatment as appropriate for the symptoms presented. In this case, some oxygen is the only treatment indicated and the only treatment provided.
I wonder if this will lead to others reporting similar cases of mass delusions compounded by
Magic 8 Ball RAD-57 readiongs.
See also –
Toxic exposure or mass sociogenic illness? The diagnosis can be challenging
The Poison Review
February 18, 2012, 12:28 am
Mass psychogenic illness attributed to toxic exposure at a high school.
Jones TF, Craig AS, Hoy D, Gunter EW, Ashley DL, Barr DB, Brock JW, Schaffner W.
N Engl J Med. 2000 Jan 13;342(2):96-100.
PMID: 10631279 [PubMed – indexed for MEDLINE]
 Mass sociogenic illness initially reported as carbon monoxide poisoning.
Nordt SP, Minns A, Carstairs S, Kreshak A, Campbell C, Tomaszweski C, Hayden SR, Clark RF, Joshua A, Ly BT.
J Emerg Med. 2012 Feb;42(2):159-61. Epub 2011 Jun 11.
PMID: 21658882 [PubMed – in process]
Nordt, S., Minns, A., Carstairs, S., Kreshak, A., Campbell, C., Tomaszweski, C., Hayden, S., Clark, R., Joshua, A., & Ly, B. (2012). Mass Sociogenic Illness Initially Reported as Carbon Monoxide Poisoning The Journal of Emergency Medicine, 42 (2), 159-161 DOI: 10.1016/j.jemermed.2011.01.028